2-(Trifluoromethoxy)phenylboronic acid

2-(Trifluoromethoxy)phenylboronic acid - Names and Identifiers

Name	2-(Trifluormethoxy)phenylboronic acid
Synonyms	AKOS BRN-0449 RARECHEM AH PB 0077 2-(Trifluoromethoxy)Phenylboro 2-(Trifluormethoxy)phenylboronic acid 2-(TRIFLUORMETHOXY)PHENYLBORONIC ACID 2-(Trifluoromethoxy)phenylboronicacid O-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID 2-(Trifluoromethoxy)phenylboronic acid 2-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID 2-(TRIFLUOROMETHOXY)BENZENEBORONIC ACID 2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)
CAS	175676-65-0
InChI	InChI=1/C7H6BF3O3/c9-7(10,11)14-6-4-2-1-3-5(6)8(12)13/h1-4,12-13H
InChIKey	AIJCNTOYZPKURP-UHFFFAOYSA-N

2-(Trifluoromethoxy)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C7H6BF3O3
Molar Mass	205.93
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	118-120°C
Boling Point	267.2±50.0 °C(Predicted)
Flash Point	110℃
Vapor Presure	0.00411mmHg at 25°C
Appearance	Powder or Crystalline Powder
Color	White to pale brown
BRN	8766167
pKa	8.14±0.53(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.461
MDL	MFCD01320763
Physical and Chemical Properties	Storage Conditions: Keep Cold

2-(Trifluoromethoxy)phenylboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29163990
Hazard Note	Irritant
Hazard Class	MOISTURE SENSITIVE,

2-(Trifluoromethoxy)phenylboronic acid - Introduction

2-(Trifluormethoxy)phenylboronic acid is an organic boron compound with the chemical formula C7H5BF3O2. The following is a description of its nature, use, preparation and safety information:

Nature:
2-(Trifluormethoxy)phenylboronic acid is a colorless to yellow crystal with good solubility. It is a strong Lewis acid that can form adducts with Lewis bases. The compound can be decomposed at high temperature.

Use:
2-(Trifluormethoxy)phenylboronic acid is an important intermediate in the synthesis of organic compounds. It is widely used in the construction of carbon-carbon bonds, reduction, oxidation and ligand reaction in organic synthesis. It is also used in the field of medicine synthesis.

Method:
2-(Trifluormethoxy)phenylboronic acid has various preparation methods, and the common method is to generate it by reacting phenylboronic acid with trifluoromethyl alcohol.

Safety Information:
When operating and handling 2-(Trifluormethoxy)phenyl boronic acid, you need to pay attention to the following security matters:
1. The compound may cause irritation to the eyes, skin and respiratory system, so wear appropriate protective equipment to protect the eyes, skin and respiratory system.
2. Avoid direct contact and inhalation, and operate under well-ventilated conditions.
3. In the use and storage process should pay attention to fire and explosion prevention measures.
4. In case of contact and ingestion, rinse immediately with plenty of water and seek medical help.
5. During storage and handling, avoid contact with strong oxidants and strong acids.

Last Update：2024-04-09 20:49:11